Description

Technical Parameters

5- Amino-1-methylquinoline (5-amino-1MQ) 5mg/vial core introduction

Pharmaceutical -grade small molecule compounds | Made in China: 5-amino-1-methylquinoline (NNMT inhibitor )

Chemical name : 5-amino-1-methylquinoline

CAS Number : ** 855427-87-1

Specification : 5mg/bottle

Dosage form : Lyophilized powder for injection

Molecular formula : C₁₀H₁₀N₂

Molecular weight : 158.20

Melting point : 195-198℃

Appearance : White to off-white lyophilized powder

Purity : ≥98% (HPLC detection)

Storage conditions : Store at -20℃ away from light.

Core Effects

5-Amino-1-methylquinoline is a selective nicotinamide N-methyltransferase (NNMT) inhibitor . Due to its unique metabolic regulation mechanism , it is widely used in metabolic disease research, obesity treatment research, and anti-aging application research .

✅ NNMT inhibition mechanism :

Metabolic reprogramming : Inhibiting NNMT activity and regulating NAD+ metabolic pathways

Energy expenditure : Increases energy expenditure and promotes fat oxidation.

Insulin sensitivity : Improves insulin sensitivity and regulates blood sugar stability.

✅ The quality advantages of "Made in China" :

Purity Guaranteed : Chemically synthesized, purity ≥98%, single impurities ≤0.1%

Crystal form control : Stable alpha crystal form ensures bioavailability.

Chiral purity : No chiral centers, well-defined structure.

✅ Global supply assurance :

Cold chain logistics : -20℃ cold chain transportation throughout the entire process to ensure product stability.

Multi- warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 10 days.

Customs clearance support : Complete export documents such as MSDS and COA.

Production process and quality assurance

1. Advantages of the synthesis process :

Chemical synthesis : A multi-step organic synthetic route was adopted, with an overall yield >85%.

Purification process : Column chromatography combined with recrystallization to obtain high-purity products.

Freeze-drying technology : temperature-controlled freeze-drying, moisture content ≤3.0%.

2. Strict quality control standards :

Chemical purity :

Main component content: 98.0%~102.0%

Related substances: Single impurity ≤0.1%, total impurities ≤0.5%

Residual solvent: Complies with ICH Q3C standards

Physical properties :

Solution transparency: Meets the requirements for injectable formulations.

pH value: 6.0-7.5

Bacterial endotoxin: <0.5 EU/mg

3. Stability data :

Long-term stability : After being stored at -20℃ for 24 months, all indicators met the requirements.

Accelerated testing : After being stored at 40℃ for 3 months, the purity decreased by ≤1.0%.

Stability in use : After reconstitution, store at 2-8℃ for 7 days; purity ≥95%.

Scientific Research Applications and Mechanisms

1. Mechanism of action :

NNMT inhibition : Specifically inhibits NNMT, reducing NAM methylation.

NAD + Boost : Increases intracellular NAD+ levels and activates sirtuins.

Metabolic Improvement : Improves mitochondrial function and enhances fatty acid oxidation.

2. Research Applications :

Obesity research : Energy metabolism study in a diet-induced obesity model

Metabolic Diseases : Insulin Sensitivity Studies in Type 2 Diabetes

Anti- aging research : Research on the mechanisms of aging-related metabolic changes

3. Preclinical data :

Weight loss effect : Animal experiments show significant weight loss.

Metabolic improvement : Improved glucose tolerance and insulin sensitivity

Safety : Preclinical studies show a good safety window.

Global supply and service assurance

1. Production capacity :

Annual production capacity : Over 1 kg per year

Flexible manufacturing : Customized specifications and packaging requirements are acceptable.

Production capacity assurance : Multiple production lines ensure stable supply.

2. Quality Certification :

System Certification : Certified by ISO 9001 Quality Management System

Compliance with standards : Meets pharmaceutical raw material standards

Complete documentation : Provides a complete package of high-quality documentation.

3. Logistics support :

Cryogenic Packaging : Dry ice is used for transportation, and the temperature is maintained at -70℃ for ≥72 hours.

Real-time monitoring : Equipped with a temperature recorder, temperature data can be traced throughout the entire process.

Emergency Plan : Establish an emergency response mechanism for abnormal situations.

Why choose 5-amino-1-methylquinoline manufactured in China ?

Novel Mechanism : NNMT Inhibitors with Unique Metabolic Regulatory Effects

Purity Guaranteed : Over 98% high purity, with strict impurity control.

Research-grade quality : Meets the standards for compounds used in scientific research

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summary

Made in China, 5-amino-1-methylquinoline 5mg lyophilized powder for injection represents a high-quality standard in metabolic regulator research . Through advanced synthesis processes, rigorous quality control, and a stable supply system , it provides high-quality, highly active research tools for global research in metabolic diseases and anti-aging . Choosing Made in China means choosing research-grade quality and reliable assurance .

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