China Cagrilintide 5mg+Semaglutide 5mg 10mg/vial Peptides Freeze-dried Powder

Cagrilintide 5mg + Semaglutide 5mg 10mg/bottle: Key Information

Pharmaceutical -grade dual-peptide formulation | Long-acting hypoglycemic and depressant formulation made in China (GLP-1/amylin dual agonist )

Ingredient specifications :

Cagrilintide : 5mg/vial (long-acting amylin analogue)

Semaglutide : 5mg/bottle (long-acting GLP-1 analog)

Total content : 10mg/bottle

Dosage form : Lyophilized powder for injection

Appearance : White freeze-dried lumpy powder

Purity : The purity of each component is ≥98% (HPLC analysis).

Core Effects

This dipeptide combination preparation is a dual agonist of GLP-1 receptor and amylin receptor . Due to its unique mechanism of synergistic regulation of appetite and metabolism , it is widely used in the treatment of type 2 diabetes, obesity management, and improvement of metabolic syndrome .

✅ Dual synergistic mechanism :

Semaglutide : GLP-1 receptor agonist, promotes insulin release, inhibits glucagon, and delays gastric emptying.

Cagrilintide : Acts on amylin receptors, enhances satiety, reduces food intake, and synergistically aids in weight loss.

Synergistic effect : The dual pathways work synergistically, resulting in better weight loss than monotherapy.

✅ The quality advantages of "Made in China" :

Purity Guaranteed : Solid-phase synthesis process is used, purity ≥98%, single impurity ≤0.1%.

Activity confirmation : In vitro activity EC50 < 0.1 nM, high in vivo potency.

Excellent stability : Accelerated testing showed that the purity remained above 97% for 6 months.

✅ Global supply assurance :

Cold chain logistics : 2-8℃ cold chain transportation throughout the entire process to ensure product stability.

Multi- warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 7 days.

Customs clearance support : Professional document preparation ensures smooth customs clearance worldwide.

Characteristics of each component and synergistic effects

1. Semaglutide :

Sequence ​: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

Molecular weight : 4113.6 Da

Characteristics : Long-acting GLP-1 analog with a half-life of approximately 7 days.

2. Cagrilintide :

Sequence : Patent-protected sequence (amylin analogue)

Molecular weight : Approximately 3.9 kDa

Features : Long-acting amylin analogue, enhances satiety, and reduces food intake.

3. Synergistic advantages :

Weight loss effect : Phase III clinical trials showed that combination therapy improved weight loss by 30-40%.

Metabolic Improvement : Synergistically improves blood sugar, blood lipids, and blood pressure.

Convenient medication administration : Once-weekly dosing improves patient compliance.

Production process and quality assurance

1. Advanced synthesis process :

Separate synthesis : Each component is synthesized independently in a solid phase to ensure sequence accuracy.

Fatty acid modification : Utilizing patented fatty acid side chain modification technology, the half-life is extended.

Freeze-drying technology : temperature-controlled freeze-drying, reconstitution time <30 seconds

2. Strict quality control standards :

Physicochemical properties :

Content: 95.0%~105.0% of the labeled amount of each component.

Relevant substances: Single impurities ≤ 0.1%, total impurities ≤ 0.5%

Polymer impurities: ≤1.0% (SEC-HPLC)

Biological activity :

Cell viability assay: titer not less than 90% of the standard.

In vivo efficacy: Meets quality standards

3. Stability data :

Long-term stability : After being stored at -20℃ for 36 months, all indicators met the requirements.

Accelerated testing : After 6 months at 40℃, purity decreased by ≤1.5%.

Stability in use : After reconstitution, store at 2-8℃ for 28 days; purity ≥95%.

Clinical advantages and application prospects

1. Clinical trial data :

Weight loss effect : Phase III clinical trials showed a weight loss of 15-20%.

Blood sugar control : HbA1c decreased by 1.5-2.0%.

Good safety profile : The incidence of adverse events is comparable to that of monotherapy.

2. Application Prospects :

Obesity treatment : Obese patients with a BMI ≥ 30 kg/m² or ≥ 27 kg/m² with complications.

Diabetes Management : Dual Management of Weight and Blood Glucose in Patients with Type 2 Diabetes

Metabolic Improvement : Improves metabolic complications such as dyslipidemia and non-alcoholic fatty liver disease.

Global supply and service assurance

1. Supply chain advantages :

Raw material supply : Self-built peptide raw material production base with ample production capacity.

Production Compliance : Passed on-site inspections by NMPA and FDA, and meets international GMP standards.

Quality System : Establish a full traceability system from raw materials to finished products.

2. Logistics Support :

Temperature-controlled packaging : Utilizes phase change materials, maintaining a temperature of 2-8℃ for ≥72 hours.

Real-time monitoring : Equipped with a temperature recorder, temperature data can be traced throughout the entire process.

Emergency Plan : Establish an emergency response mechanism for abnormal situations.

3. Technical Services :

Professional support : Providing technical information and regulatory application support.

Customization service : We can provide customized packaging specifications according to customer needs.

After-sales guarantee : Establish a rapid response mechanism for customer complaints.

Why choose a Chinese-made dipeptide compound preparation ?

Innovative Combination : The First GLP-1/Amylin Dual Agonist Combination Formulation

Reliable Quality : Manufactured in strict accordance with international GMP standards, ensuring controllable quality.

Synergistic effect : Dual mechanism of action, significantly better weight loss effect than single drug.

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summarize

The Cagrilintide + Semaglutide dual-peptide combination formulation made in China represents a new breakthrough in the treatment of metabolic diseases . Through precise formulation design, rigorous quality control, and a comprehensive supply chain system , it provides more effective and convenient treatment options for obese and diabetic patients worldwide . Choosing Made in China means choosing innovative quality and reliable assurance .

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