Dermorphin 5mg/bottle core introduction
High-purity corticomerol raw material | Made in China, potent μ-opioid receptor agonist 5mg/bottle
Generic name : Piperamide
English name : Dermorphin
Amino acid sequence : H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂
CAS No .: 77614-16-5
Molecular formula : C₄₀H₅₀N₈O₁₀
Molecular weight : 802.89 g/mol
Purity : ≥98.0% (HPLC)
Appearance : White lyophilized powder
Storage : Freeze at -20℃, protect from light, and store in a dry place.
Usage and Storage Guide
1. Reconstitution and preparation :
Recommended solvent :
Preferred solvent : 1% aqueous acetic acid solution or 0.1M hydrochloric acid solution
Secondary solvent : Sterile water for injection (please pay attention to solubility).
For cell experiments : dissolve in a small amount of dilute acid first, then dilute with PBS or culture medium.
Standard preparation procedure :
Solvent preparation :
Return the 1% acetic acid solution or sterile water to room temperature.
It is recommended to add 0.1% bovine serum albumin (BSA) to reduce adsorption.
Reconstitution procedure :
Add 1.0 mL of solvent to a 5 mg vial.
Gently rotate the vial to dissolve it completely.
Final concentration: 5 mg/mL (approximately 6.2 mM)
Separate and store :
Immediately dispense into 10-20 μL portions.
Label concentration, date, batch
Preparation of working solution :
In vitro cell experiments : working concentration 0.1-10 nM
Animal studies : Recommended dose 1-10 μg/kg
Note : Avoid repeated freeze-thaw cycles; use fresh aliquots for each experiment.
Key points to note :
Dissolving tips : An acidic environment (pH 3-4) is conducive to dissolution.
Avoid adsorption : Use pipes with low adsorption properties
Aseptic technique : Strict aseptic technique must be maintained during the preparation process.
Use immediately : Use within 1 hour after reconstitution.
Safety precautions : Wear gloves and a mask during operation.
2. Storage conditions :
Unreconstituted lyophilized powder :
Long-term storage : Store frozen at -20℃, shelf life 24 months
Optimal storage : Store frozen at -80°C; shelf life 36 months.
Light protection requirement : Store in the original aluminum foil bag away from light.
Reconstituted solution :
Use immediately : Best used immediately after preparation.
Short-term storage : Refrigerate at 2-8℃ for no more than 4 hours.
Long-term storage : Aliquot and freeze at -20℃ for no more than 1 month.
Transportation conditions :
Freeze-dried powder : transported with dry ice (below -78℃).
Short-term transportation : Ice pack transportation (2-8℃)
Light-proof packaging : Light-proof materials must be used.
3. Preparation details guide :
Solvent selection principles :
Prefer acidic solvents
Avoid using alkaline buffer solutions.
Recommended 1% acetic acid solution
Dissolution method :
Add solvent slowly
Gentle rotational dissolution
Avoid violent oscillations
Concentration control :
Stock solution concentration 5 mg/mL
Prepare working solution fresh each time.
Avoid high dilution storage
Storage tips :
Dispense volume 10-20 μL
Clear and complete markings
Store separately in a sealed container
4. Special Notes :
Biosafety :
Operating in a dedicated fume hood
Avoid direct skin contact
Specialized waste liquid treatment
stability :
It is sensitive to light and needs to be kept away from light.
Sensitive to heat, avoid high temperatures.
Sensitive to enzymes, please store carefully.
Compatibility :
Compatible with acidic solvents
Avoid contact with oxidants
It does not coexist with metal ions
Quality Advantages of Chinese Manufacturers
This product is manufactured by a professional peptide producer in China, strictly adhering to cGMP standards, and its quality has reached the international advanced level.
✅Advanced Synthesis Technology :
Fmoc solid-phase synthesis : using microwave-assisted technology
D-Amino Acid Proprietary Technology : Precise Introduction of D-Alanine
Mass production : batch sizes up to 10 grams
Fully automated control : ensuring synthesis accuracy
✅Strict quality control :
Purity testing :
HPLC purity ≥ 98.0%
Chiral purity D-Ala ≥ 99.5%
Single impurity ≤ 0.5%, total impurities ≤ 2.0%
Structural confirmation :
MALDI-TOF MS mass spectrometry analysis
Amino acid composition analysis
Sequence verification
Bioactivity :
GPCR activity detection
IC₅₀≤0.1nM
Selective Validation
Security check :
Bacterial endotoxin <10 EU/mg
Passed sterility test
Heavy metals <10ppm
Physicochemical properties :
Moisture content ≤ 5.0%
Peptide content ≥ 80.0%
Complete solubility
✅Stability Guaranteed :
Accelerated testing : Stable for 3 months at 40℃/75%RH
Long-term test : Stable at -20℃ for 24 months
Photostability : Stable under light-protected conditions
Thermal stability : Stable under refrigeration conditions
✅Professional Packaging :
Vial : Amber-colored light-blocking glass
Sealing system : Fluorinated butyl rubber stopper
Nitrogen purging protection : to prevent oxidation
Individual packaging : Individual aluminum bag + desiccant
Complete tags : Complete information in both Chinese and English
✅Technical Support :
Provide complete technical documentation
Including COA, MSDS
Custom synthesis service
Application technical support
Need anything, please contact us
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+852 4671 8216 |
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Telegram |
Allenraws |
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Allenraws810@gmail.com |

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