CJC1295 With DAC 2mg/vial Continuous Support For Muscle Growth And Repair

CJC-1295 (containing DAC) 2mg/vial core introduction

Long-acting growth hormone-releasing hormone analogue | Drug affinity complex modified peptide 2mg/vial

Generic name : CJC-1295 (containing drug affinity complex)

English name : CJC-1295 (with Drug Affinity Complex)

Sequence : GRF(1-29) modified peptide

Molecular weight : Approximately 4500 Da

Purity : ≥98.0% (HPLC)

Content : 2mg/bottle

Appearance : White lyophilized powder

Storage : Freeze at -20℃, protect from light, and store in a dry place.

Usage and Storage Guide

CJC-1295 (containing DAC) long-acting growth hormone-releasing hormone analog:

CJC-1295 (containing DAC) is a modified growth hormone-releasing hormone (GHRH) analog that significantly prolongs its half-life through covalent binding to the drug affinity complex (DAC). This structural modification allows it to reversibly bind to albumin in the blood, achieving a sustained-release effect. In experimental animal models, a single dose can maintain the growth hormone-releasing effect for several days. In exercise physiology studies, this peptide has unique value in studying the long-term maintenance of anabolic states and the promotion of sustained protein synthesis due to its ability to produce sustained and stable levels of endogenous growth hormone.

In studies of muscle metabolism and recovery mechanisms, long-acting CJC-1295, due to its ability to mimic a sustained growth hormone secretion pattern, has been used to evaluate the role of growth hormone in promoting long-term lean body mass accumulation, supporting high-intensity training adaptation, and maintaining an anti-catabolic environment. It provides controlled experimental conditions for investigating how to improve athletic performance and promote training recovery by prolonging the duration of endogenous growth hormone action.

CJC-1295 (including DAC) Applications:

As a long-acting growth hormone-releasing hormone analog, it is mainly used to study the effects of sustained growth hormone release on long-term muscle protein synthesis, lipid metabolism regulation, and exercise adaptation maintenance. It is an important experimental tool for studying the long-term effects of growth hormone and assessing its long-term improvement in body composition during training.

It is applied to studies on sustained growth hormone release, assessment of long-term anabolism effects, analysis of exercise adaptation maintenance mechanisms, and research on the role of endogenous growth hormone in supporting high-intensity training cycles, promoting long-term muscle growth, and optimizing body composition.

Usage and Storage Methods

1. Reconstitution and preparation :

Recommended solvent :

Preferred solvent : sterile water for injection

Carrier solution : diluted with sterile physiological saline for in vivo studies.

Important note : Optimal stability is observed in neutral buffer solutions (pH 7.2-7.6).

Standard preparation procedure :

Solvent preparation :

Sterile water for injection, aseptically filtered through a 0.22 μm filter membrane.

Allow the solvent temperature to return to room temperature (20-25℃).

Reconstitution procedure :

Add 1.0-2.0 mL of sterile water for injection to a 2 mg vial.

Slowly pour the powder along the bottle wall to avoid direct impact on the powder.

Gently rotate the vial for 3-5 minutes until completely dissolved.

Final concentration: 2 mg/mL or 1 mg/mL

Dispensing and dilution :

Immediately dispense into single-use doses using low-absorption cryovials.

Dilute with sterile saline to the required working concentration.

Clear labeling: Name, concentration, preparation date, batch number

Working concentration/dosage reference :

In vitro cell experiments : concentration range 0.1-100 nM, preliminary experiments are required for optimization.

Animal experiments :

Subcutaneous injection : The usual dose is 1-5 μg/kg, and the frequency of administration is relatively low.

Determine the precise dosage based on the specific model and experimental objectives.

Example of preparation calculation : If a 100 μg/mL working solution is required, take 0.05 mL of stock solution (2 mg/mL) and add it to 0.95 mL of physiological saline.

Key points to note :

Avoid violent shaking; gently rotate to dissolve.

Strict aseptic technique

Light-proof treatment throughout the process

It is recommended to prepare and use immediately.

Use low-adsorption laboratory consumables

2. Storage conditions :

Unreconstituted lyophilized powder :

Long-term storage: Frozen at -20℃, shelf life 24 months

Optimal storage: -80°C (deep freeze), shelf life 36 months.

Strictly protect from light: Store in the original light-proof aluminum foil bag.

Moisture protection: Built-in desiccant

Reconstituted solution :

Use immediately: For best activity, use immediately after reconstitution.

Short-term storage: Refrigerate at 2-8℃ away from light, for no more than 24 hours.

Repackage and freeze: Store at -20℃ or -80℃ away from light, for no more than 1 week.

Repeated freeze-thaw cycles are strictly prohibited: a maximum of one freeze-thaw cycle.

Transportation conditions :

Freeze-dried powder: transported with dry ice (-78℃)

Short-term transportation: 2-8℃ ice pack transportation

Packaging: Light-proof aluminum foil bag + vacuum seal + foam insulated box

3. Stability and Processing Standards :

Chemical and physical stability :

Relatively stable under neutral pH conditions

Avoid contact with strong acids, strong alkalis, and oxidizing agents.

Sensitive to high temperature

Maintenance of bioactivity :

Proper dispensing and low-temperature storage are key.

Avoid repeated freeze-thaw cycles

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