Description

Technical Parameters

AOD9604 Peptide Raw Material 2mg/bottle Core Introduction

Pharmaceutical-grade peptide raw material | Made in China AOD9604 (growth hormone fragments 176-191 )

Chemical name : Tyrosine-Leucine-Arginine-Isoleucine-Valine-Glutamine-Cysteine-Arginine-Serine-Valine-Aspartic Alanine-Cysteine-Phenylalanine

Sequence : H-Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Asp-Ala-Cys-Phe-OH (Disulfide Bridge: Cys7-Cys13)

CAS No .: 221231-10-3

Specification : 2mg/bottle (lyophilized powder)

Dosage form : Lyophilized powder for injection raw material

Molecular formula : C₇₈H₁₂₂N₂₂O₂₂S₂

Molecular weight : 1815.04 Da

Purity : ≥98% (HPLC detection)

Storage temperature : -20℃ for long-term storage, 2-8℃ for short-term storage

Reconstituted storage : refrigerate at 2-8℃ and use within 7 days.

Core Effects

AOD9604 is a synthetic C-terminal fragment of growth hormone (amino acid sequence 176-191) . Due to its unique fat-decomposing properties and safe pharmacological effects , it is widely used in fat metabolism research, obesity treatment exploration, and body fat management .

✅Targeted mechanism of action :

Fat breakdown : Specifically promotes the breakdown and metabolism of fat cells

Receptor function : Mediates lipolysis through β3-adrenergic receptors.

Metabolic regulation : Regulating lipid metabolism-related signaling pathways

✅Quality advantages of Chinese manufacturing :

Solid-phase synthesis process : Fmoc solid-phase synthesis technology is used, with a condensation efficiency >99.5%.

Purification techniques : Preparative HPLC purification, gradient elution, collection of the main peak.

Freeze-drying process : Vacuum freeze-drying, residual moisture ≤3.0%

✅Quality Analysis Standards :

HPLC purity : ≥98% (C18 column, acetonitrile-water gradient elution)

Mass spectrometry confirmation : MALDI-TOF MS confirms molecular weight

Peptide mapping analysis : LC-MS/MS sequencing was performed after trypsin digestion.

Disulfide bond verification : Ellman's reagent method confirms disulfide bond formation.

Product Features and Advantages

1. Advantages in scientific research applications :

Highly targeted : specifically acts on lipid metabolism pathways

High safety : No systemic effects of growth hormone

Mechanism clearly defined : The mechanism of action has been elucidated by multiple studies.

Model validation : Validating the effect in multiple animal models.

2. Technical parameters :

Appearance : White, loose, lyophilized powder

Solubility : Easily soluble in water for injection or physiological saline.

Isoelectric point : pH 6.8-7.2

Extinction coefficient : ε280 = 6970 M⁻¹cm⁻¹

3. Advantages of Chinese manufacturing :

Cost-effectiveness : Large-scale production provides a competitive advantage

Stable supply : a complete peptide synthesis industry chain

Customized services : We can provide customized services based on your research needs.

Technical support : Professional technicians provide application guidance.

Usage and Storage Guide

1. Storage conditions :

Long-term storage : Store below -20℃, protected from light. Shelf life: 24 months.

Short-term storage : Can be stored for 30 days when refrigerated at 2-8℃.

After rehydration : Store at 2-8℃ for no more than 7 days, avoiding repeated freeze-thaw cycles.

Transportation conditions : Transport with ice packs, temperature controlled between 2-8℃

2. Reconstitution method :

Preparation : Remove the freeze-dried powder and allow it to equilibrate at room temperature for 15 minutes.

Diluent selection : Sterile water for injection or physiological saline is recommended.

Reconstitution procedure : Slowly pour 1 ml of diluent along the wall of the bottle and gently rotate to dissolve.

Concentration calculation : 2mg/1ml = 2mg/ml working concentration

Sterilization filtration : If necessary, a 0.22μm filter membrane can be used for filtration.

3. Usage suggestions :

Study dosage : The recommended dosage range is 100-300 μg/kg body weight/day

Administration method : subcutaneous injection or intraperitoneal injection

Study period : 4-12 weeks of continuous use is recommended.

Observation indicators : body fat percentage, blood lipid levels, glucose metabolism, etc.

4. Precautions :

To avoid contamination : All operations should be performed in a clean environment.

Do not shake : Avoid vigorous shaking during reconstitution to prevent protein denaturation.

Prepare and use immediately : It is recommended to use as soon as possible after reconstitution.

Equipment requirements : Use sterile syringes and needles.

Research and application directions

1. Basic research field :

Research on the regulatory mechanism of lipid metabolism

β3 adrenergic receptor function study

Exploration of lipolysis signaling pathways

2. Applied research areas :

Development of obesity treatment methods

Metabolic syndrome intervention study

Research and development of sports nutrition supplements

3. Preclinical studies :

Animal model pharmacodynamic studies

Toxicological safety assessment

Pharmacokinetic characteristics study

Why choose AOD9604 made in China ?

Professional Synthesis : Mature solid-phase synthesis technology ensures accurate sequence.

Strict quality control : Multiple analytical methods ensure product quality

Supply Guarantee : Large-scale production capacity ensures stable supply

Technical Support : Comprehensive support provided by a professional technical team.

Summary

This product is a high-purity AOD9604 peptide raw material , produced using advanced Chinese solid-phase synthesis technology and a rigorous quality control system . It provides a high-quality, highly active research tool for lipid metabolism-related scientific research . With proper storage and use , researchers can obtain reliable and reproducible experimental results .

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