Description

Technical Parameters

Adipotide 2mg/bottle core introduction

Pharmaceutical-grade peptide formulation | Chinese-made fat-targeting peptide (Adipotide )

Chemical name : CKGGRAKDC-GG-D(KLAKLAK)2

Sequence structure :

Target domain : CKGGRAKDC (targets adipocytes)

Connection domain : Gly-Gly

Effect domain : D(KLAKLAK)2 (pro-apoptotic peptide)

CAS Number : Unknown (Sequence Peptide)

Specification : 2mg/bottle

Dosage form : Lyophilized powder for injection

Molecular weight : Approximately 3,200 Da

Appearance : White freeze-dried lumpy powder

Purity : ≥95% (HPLC detection)

Storage conditions : Store at -20℃ away from light.

Core Effects

Adipotide is a pro-apoptotic peptide that targets fat . Due to its unique bifunctional structure , it is widely used in research on localized fat reduction, obesity treatment, and metabolic diseases .

✅ Dual mechanism of action :

Targeted delivery : CKGGRAKDC domain specifically binds to adipocyte surface proteins

Induction of apoptosis : The KLAKLAK domain disrupts the mitochondrial membrane, inducing apoptosis.

Targeted fat reduction : precisely targets specific fat areas to reduce localized fat accumulation.

✅Quality advantages of Chinese manufacturing :

Purity Guaranteed : Solid-phase synthesis process, purity ≥95%, single impurities ≤0.5%.

Structural accuracy : The correct assembly rate of the dual-function structure is ≥98%.

Activity confirmation : In vitro apoptosis assay EC50 < 1 μM

✅Global supply assurance :

Cold chain logistics : -20℃ cold chain transportation throughout the entire process to ensure product stability.

Multi-warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 7 days.

Customs clearance support : Professional document preparation ensures smooth customs clearance worldwide.

Production process and quality assurance

1. Advanced synthesis process :

Segmented synthesis : The target domain and effector domain are synthesized separately, with purity controlled.

Connection Assembly : The Gly-Gly connection domain accurately connects two functional domains.

Purification process : Preparative HPLC purification, gradient elution, collection of the main peak.

2. Strict quality control standards :

Chemical purity :

Main component content: 95.0%~105.0%

Related substances: Single impurity ≤ 0.5%, total impurities ≤ 1.0%

Acetic acid content: ≤10.0% (ion chromatography)

Biological activity :

Cell-targeted assay: Targeting efficiency not less than 90% of the standard.

Apoptosis induction assay: The apoptosis rate met the quality standard requirements.

3. Stability data :

Long-term stability : Stored at -20℃ for 24 months, all indicators meet the requirements.

Accelerated testing : After 6 months at 25°C, the purity decreased by ≤3.0%.

Stability in use : After reconstitution, store at 2-8℃ for 7 days; purity ≥90%.

Scientific Research Applications and Clinical Prospects

1. Mechanism of action study :

Fat targeting : Target domain specifically binds to proteins on the surface of adipocytes

Apoptosis : Effect domain induces programmed cell death in adipocytes

Targeted fat reduction : precisely reduce fat accumulation in specific areas.

2. Research and application areas :

Obesity Treatment : Targeted Therapy Research on Localized Fat Accumulation

Metabolic diseases : A study on the treatment of obesity-related metabolic syndrome

Aesthetic Medicine : Research on the Application of Localized Body Shaping and Fat Reduction

3. Preclinical data :

Fat reduction effect : Animal experiments show a 30-40% reduction in localized fat.

Targeted action : Primarily targets white adipose tissue, with minimal impact on muscle tissue.

Safety : Wide therapeutic window, manageable side effects.

The Quality Advantages of Made in China

1. Advantages in manufacturing process :

Synthesis technology : Microwave-assisted solid-state synthesis with high condensation efficiency.

Purification process : Preparative HPLC purification, purity ≥ 95%

Quality control : Quality control throughout the entire process from raw materials to finished products.

2. Quality Assurance System :

Compliant with standards : Meets Chinese Pharmacopoeia, USP, and EP standards.

Stability study : Complete a comprehensive stability investigation.

Batch consistency : Strict process control ensures consistency between batches.

3. Global supply network :

Production Base : GMP-compliant production base in China

Distribution network : A global distribution and cold chain logistics network

Registration support : Supports registration applications from countries around the world.

Why choose Adipotide, made in China ?

Innovative Mechanism : The first fat-targeting pro-apoptosis peptide with a unique mechanism.

High purity : Over 95% purity, with strict quality control.

Highly targeted : Specifically targets adipocytes, reducing side effects.

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summary

Made in China, Adipotide 2mg lyophilized powder for injection represents a high-quality standard for targeted therapeutic peptides . Through advanced synthesis processes, rigorous quality control, and a stable supply system , it provides high-quality, highly active research tools for global research on obesity and metabolic diseases . Choosing Made in China means choosing research-grade quality and reliable assurance .

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