Description

Technical Parameters

GW0742 Raw Material Powder Core Introduction

Pharmaceutical-grade raw material | Made in China GW0742 (PPARδ agonist )

Chemical name : (2S)-2-(4-{[(1,1'-diphenyl)-2-yl]amino}phenyl)propionic acid

CAS No .: 317318-70-0

EINECS ID : -

Molecular formula : C₂₁H₁₉F₃N₂O₃S

Molecular weight : 424.45

Melting point : 189-192℃

Appearance : White crystalline powder

Purity : ≥99% (HPLC detection)

Core Effects

GW0742 is a highly selective PPARδ agonist that is widely used in metabolic disease research, exercise endurance improvement, and muscle endurance enhancement due to its unique peroxisome proliferator-activated receptor δ-regulatory properties .

✅Metabolic regulation mechanism :

PPARδ activation : Highly selectively activates the PPARδ nuclear receptor, EC50 = 1 nM

Fatty acid oxidation : Promotes fatty acid β-oxidation, increasing energy expenditure.

Improved glucose metabolism : Improved insulin sensitivity and regulation of glucose metabolism

✅Quality advantages of Chinese manufacturing :

Purity Guarantee : Raw material purity ≥ 99.5%, conforming to USP standards.

Chirality control : (S)-configuration optical purity ≥ 99.8%

Excellent stability : Purity remains above 97% after 6 months of accelerated testing.

✅Global supply assurance :

Cold chain logistics : -20℃ cold chain transportation throughout the entire process to ensure product stability.

Multi-warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 7 days.

Customs clearance support : Professional document preparation ensures smooth customs clearance worldwide.

Production process and quality assurance

1. Advanced synthesis process :

Chiral synthesis : Asymmetric synthesis, (S)-configuration optical purity ≥99.8%

Purification process : Preparative HPLC purification, gradient elution, collection of the main peak.

Drying technology : Vacuum low-temperature drying, moisture content ≤0.5%

2. Strict quality control standards :

Chemical purity :

Main component content: 99.0%~101.0%

Related substances: Single impurity ≤0.1%, total impurities ≤0.5%

Residual solvent: Complies with ICH Q3C standards

Physical properties :

Particle size distribution: D50 50-100μm

Bulk density: 0.4-0.6 g/cm³

Solubility: Meets the standards for active pharmaceutical ingredients.

3. Stability data :

Long-term stability : Stored at -20℃ for 24 months, all indicators meet the requirements.

Accelerated testing : After being stored at 25°C for 6 months, the purity decreased by ≤2.0%.

Transportation stability : Vibration and drop tests passed.

Application characteristics and advantages

1. Efficacy characteristics :

Endurance Enhancement : Significantly improves exercise endurance and maximum oxygen uptake.

Fat reduction : Promotes fat oxidation and reduces body fat.

Metabolic improvements : Improved blood sugar control and insulin sensitivity

2. Key Features and Advantages :

High selectivity : 1000 times higher selectivity for PPARδ than for PPARα and PPARγ.

Metabolic regulation : regulating fatty acid oxidation and energy metabolism

Good safety profile : Preclinical studies have shown good safety profile.

3. Advantages of use :

Effective orally : High oral bioavailability and easy to use.

Research Applications : An ideal tool for research in metabolic diseases and sports medicine.

Great potential : Therapeutic potential for metabolic syndrome and type 2 diabetes

Why choose the Chinese-made GW0742 ?

High selectivity : PPARδ selectivity is 1000 times higher than PPARα/γ selectivity.

Chiral purity : (S)-configuration optical purity ≥ 99.8%

Exceptional purity : Over 99% high purity, with strict quality control.

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summary

Made in China, GW0742 raw material powder represents the high-quality standard of highly selective PPARδ agonists . Through advanced chiral synthesis technology, rigorous quality control, and a stable supply system , it provides high-quality, highly active research tools for global metabolic disease and sports medicine research . Choosing Made in China means choosing research-grade quality and reliable assurance .

Need anything, please contact us