Description

Technical Parameters

PEG-MGF 2mg/vial core introduction

Pharmaceutical-grade peptide formulations | Made in China PEG-MGF 2mg/ vial

Chemical name : Polyethylene glycol-modified insulin-like growth factor-1Ec (IGF-1Ec)

Specifications : 2mg/bottle, 10 bottles/box

Molecular weight : Approximately 12,000 Da (including PEG modification)

PEG molecular weight : 20 kDa linear polyethylene glycol

Modification site : N-terminal specific PEG modification

Appearance : White lyophilized powder

Purity : ≥98% (SEC-HPLC detection)

Activity : Verification of IGF-1 receptor binding activity

Storage : Store at -20℃ for long periods, or at 2-8℃ for short periods. Avoid repeated freeze-thaw cycles.

Core Quality and Service Advantages of PEG-MGF

This product is manufactured by a Chinese cGMP-certified biotechnology company . It utilizes recombinant protein expression and site-directed PEG modification technology to provide global customers with high-purity, long-half-life growth factor products , and is equipped with a comprehensive quality control and technical support system .

✅China 's technological advantages in manufacturing :

Site-specific modification : N-terminal specific PEGylation to maintain biological activity

High purity : SEC-HPLC purity ≥98%, monomer content ≥95%.

Low endotoxin level : <0.1 EU/μg, meeting the standards for injection.

Complete quality control : Provides HPLC, SDS-PAGE, Western Blot, and activity detection reports.

✅Professional application features :

Long-lasting effect : PEG modification extends the half-life to 24-48 hours.

Muscle specificity : selectively acts on skeletal muscle satellite cells

Damage Repair : Promotes regeneration and repair after muscle injury.

Proliferative effect : Stimulates muscle fiber proliferation, rather than simple hypertrophy.

✅Production Technology Platform :

Expression system : Escherichia coli recombinant expression system

Purification process : Three-step purification: ion exchange + hydrophobic chromatography + molecular sieve.

Modification technology : N-terminal specific PEG modification technology

Freeze-drying process : Formula-optimized freeze-drying ensures long-term stability.

PEG-MGF Usage and Storage Guide

1. Reconstitution method :

Solvent selection : Use acetate buffer or a dedicated reconstitution solution with a pH of 4.0-5.0.

Dissolution procedure : Slowly pour 1-2 ml of buffer solution along the side of the bottle and gently rotate to dissolve.

Dissolving temperature : Dissolve slowly at 4℃, avoiding violent shaking.

Reconstitution concentration : 1 mg/ml is recommended to avoid high concentration aggregation.

2. Storage conditions :

Unreconstituted : Store at -20℃ for 12 months, or at -80℃ for 24 months.

Reconstituted : Can be stored for 7 days at 2-8℃, or for 1 month at -20℃.

Transportation conditions : Dry ice transportation, kept below -60℃

Precautions : Avoid repeated freeze-thaw cycles; it is recommended to store in smaller portions.

3. Injection method :

Injection site : Local intramuscular injection, with better results when administered near the site of injury.

Injection dosage : 50-200 μg per dose, adjusted according to muscle size.

Injection frequency : 2-3 times per week, with an interval of at least 48 hours.

Injection cycle : Usually, one cycle lasts 4-6 weeks.

4. Dosage regimen :

Small muscle groups : 50-100μg/session (such as biceps, deltoids)

Large muscle groups : 100-200μg/session (such as quadriceps femoris and latissimus dorsi)

Systemic use : Total weekly dose 200-400 μg, divided into 2-3 injections.

Recommended usage cycle : Use for 4 weeks, then stop for 2 weeks; or use for 6 weeks, then stop for 4 weeks.

PEG-MGF Quality Control Standards

1. Purity testing :

SEC-HPLC purity : Monomers ≥95%, Aggregates <3%

SDS-PAGE : Single band under reduced and non-reduced conditions

Peptide mapping analysis : Sequence verification by LC-MS/MS after trypsin digestion

PEGylation rate : >95% of molecules are modified with PEG.

2. Activity detection :

Receptor binding : IGF-1 receptor binding activity ≥80%

Cell proliferation : Experimental verification of promoting L6 myoblast proliferation

In vivo activity : experimental verification of increased muscle weight in mice

3. Physicochemical testing :

Isoelectric point : pH 5.5-6.5 (isoelectric focusing)

Circular dichroism spectroscopy : Secondary structure consistent with natural IGF-1Ec

Dynamic light scattering : Hydrated particle size 20-30nm

Zeta potential : -5 to -15 mV

Why choose PEG-MGF made in China ?

Technologically Leading : Possesses proprietary PEG modification technology

Stable quality : cGMP production, high batch-to-batch consistency

Cost advantage : Large-scale production reduces unit costs

Comprehensive Service : Provides complete technical documentation and application support

R &D Strength : Possesses continuous product optimization and development capabilities

Fitness App Guide

Applicable scenarios :

Muscle repair and recovery after high-intensity training

Assisted recovery from injuries such as muscle strains and tears.

Increase the number of muscle satellite cells and promote muscle fiber proliferation.

Intensive stimulation during the key development period of local muscles

Usage recommendations :

Local injections are most effective within 24 hours after training.

Targeted strengthening of weak muscle groups is possible.

Adequate protein and calorie intake

Ensure adequate rest and recovery during use.

Summary

This product represents the highest standards of Chinese biopharmaceutical technology . Through advanced protein engineering and modification techniques, rigorous quality control, and professional customer service , it provides high-quality, long-acting growth factor products to users worldwide . By choosing our products, you not only gain superior quality but also reliable technical support and quality assurance .

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