Description

Technical Parameters

SS-31 10mg/bottle core introduction

Pharmaceutical-grade peptide formulation | Made in China SS-31 (mitochondrial-targeting antioxidant peptide)

Chemical name : D-arginyl-D-methylphenylalanyl-L-lysyl-L-phenylalanine

Sequence : D-Arg-Dmt-Lys-Phe

CAS No .: 736992-21-5

Specification : 10mg/bottle

Dosage form : Lyophilized powder for injection

Molecular formula : C₃₀H₄₄N₈O₄

Molecular weight : 588.72

Appearance : White freeze-dried lumpy powder

Purity : ≥98% (HPLC detection)

Storage conditions : Store at -20℃ away from light.

Core Function | Core Effects

SS-31 is a mitochondrial-targeting antioxidant peptide . Due to its unique mitochondrial targeting ability and potent antioxidant properties , it is widely used for the protection of ischemia-reperfusion injury, the treatment of neurodegenerative diseases, and the recovery from exercise fatigue .

✅Mitochondrial targeting mechanism :

Targeted localization : Specifically binds to mitochondrial inner membrane cardiolipin, targeting and accumulating in mitochondria.

Antioxidant : Inhibits mitochondrial ROS production and reduces oxidative stress damage.

Membrane stability : Stabilizes mitochondrial membrane potential and improves energy metabolism.

✅Quality advantages of Chinese manufacturing :

Chiral purity : D-amino acid conformation purity ≥ 99.8%, ensuring metabolic stability.

Sequence accuracy : Solid-phase synthesis ensures 100% correct amino acid sequence.

Activity Guarantee : In vitro mitochondrial protective activity EC50 < 1 nM

✅Global supply assurance :

Cold chain logistics : -20℃ cold chain transportation throughout the entire process to ensure product stability.

Multi-warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 7 days.

Customs clearance support : Complete export documents such as MSDS and COA

Production process and quality assurance

1. Advanced synthesis process :

Solid-phase synthesis : The Fmoc solid-phase synthesis strategy was adopted, with a condensation efficiency >99.5%.

Chiral control : D-amino acid chiral purity ≥ 99.8%

Purification process : Preparative HPLC purification, gradient elution, collection of the main peak.

2. Strict quality control standards :

Chemical purity :

Main component content: 98.0%~102.0%

Related substances: Single impurity ≤0.1%, total impurities ≤0.5%

Acetic acid content: ≤10.0% (ion chromatography)

Biological activity :

Mitochondrial membrane potential protection assay: potency not less than 90% of the standard.

Cellular oxidative stress protection: Meets quality standards

3. Stability data :

Long-term stability : Stored at -20℃ for 24 months, all indicators meet the requirements.

Accelerated testing : After being stored at 25°C for 6 months, the purity decreased by ≤2.0%.

Stability in use : After reconstitution, store at 2-8℃ for 7 days; purity ≥95%.

Scientific Research Applications and Clinical Prospects

1. Mechanism of action study :

Mitochondrial targeting : Targets mitochondria by binding to cardiolipin via electrostatic interactions.

Oxidative stress protection : Inhibits mitochondrial ROS production and reduces oxidative damage.

Improved energy metabolism : Improved ATP synthesis and enhanced cellular energy supply

2. Research and application areas :

Ischemia-reperfusion : Protection against ischemia-reperfusion injury in myocardial infarction and stroke

Neurodegenerative diseases : Neuroprotective research on Alzheimer's disease and Parkinson's disease

Sports Medicine : Research on Exercise-Induced Fatigue Recovery and Muscle Damage Repair

3. Preclinical data :

Cardiac protection : Animal experiments show a 40-60% reduction in myocardial infarction area.

Neuroprotection : Improves neurological deficit scores by 30-50%.

Good safety profile : wide therapeutic window and high selectivity

Global supply and service assurance

1. Production capacity :

Annual production capacity : Over 100 grams per year

Flexible manufacturing : Customized specifications and packaging requirements are acceptable.

Production capacity assurance : Multiple production lines ensure stable supply

2. Quality Certification :

System Certification : Certified by ISO 9001 Quality Management System

Compliance with standards : Meets the standards for pharmaceutical polypeptide raw materials.

Complete documentation : Provides a complete package of quality documentation.

3. Logistics support :

Cryogenic packaging : Dry ice is used for transportation, and the temperature is maintained at -70℃ for ≥72 hours.

Real-time monitoring : Equipped with a temperature recorder, temperature data can be traced throughout the entire process.

Emergency Plan : Establish an emergency response mechanism for abnormal situations.

Why choose the Chinese-made SS-31?

Targeted Innovation : The first mitochondrial-targeting antioxidant peptide with a unique mechanism

Precise chirality : D-amino acid conformation ensures metabolic stability

Exceptional activity : Mitochondrial protective activity EC50 < 1 nM

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summarize

Made in China, SS-31 10mg lyophilized powder for injection represents a high-quality standard in mitochondrial-targeting peptide research . Through advanced chiral synthesis technology, rigorous quality control, and a stable supply system , it provides a high-quality, highly active research tool for global research on ischemia-reperfusion injury and neurodegenerative diseases . Choosing Made in China means choosing research-grade quality and reliable assurance .

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