Description

Technical Parameters

Kisspeptin-10 10mg/vial core introduction

Pharmaceutical-grade peptide formulation | Made in China Kisspeptin-10 (KISS-1 derived peptide )

Chemical name : Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe

Sequence : YNWNSFGLRF

CAS No .: 374675-21-5

Specification : 10mg/bottle

Dosage form : Lyophilized powder for injection

Molecular weight : 1,227.39 Da

Appearance : White freeze-dried lumpy powder

Purity : ≥98% (HPLC detection)

Storage conditions : Store at -20℃ away from light.

Core Effects

Kisspeptin-10 is a neuropeptide hormone that is widely used in reproductive endocrinology research, gonadal function regulation, and neuroendocrine research due to its unique hypothalamic-pituitary-gonadal axis (HPG) regulatory role .

✅ Neuroendocrine regulatory mechanism :

GnRH release : Stimulation of hypothalamus to release GnRH in a pulsatile manner

Gonadal axis activation : promotes LH and FSH secretion, regulates sex hormones

Puberty Initiation : Signaling Pathways Involved in the Initiation of Puberty Development

✅Quality advantages of Chinese manufacturing :

Purity Guaranteed : Solid-phase synthesis process, purity ≥98%, single impurities ≤0.1%.

Sequence accuracy : 100% correct amino acid sequence

Activity confirmation : cellular level GnRH release EC50 < 1 nM

✅Global supply assurance :

Cold chain logistics : -20℃ cold chain transportation throughout the entire process to ensure product stability.

Multi-warehouse delivery : Regional warehouses are established in China, Europe, America, and the Asia-Pacific region, ensuring delivery within 7 days.

Customs clearance support : Professional document preparation ensures smooth customs clearance worldwide.

Production process and quality assurance

1. Advanced synthesis process :

Solid-phase synthesis : The Fmoc solid-phase synthesis strategy was adopted, with a condensation efficiency >99.5%.

Purification process : Preparative HPLC purification, gradient elution, collection of the main peak.

Freeze-drying technology : temperature-controlled freeze-drying, moisture content ≤3.0%.

2. Strict quality control standards :

Chemical purity :

Main component content: 98.0%~102.0%

Related substances: Single impurity ≤0.1%, total impurities ≤0.5%

Acetic acid content: ≤10.0% (ion chromatography)

Biological activity :

GnRH release test: potency not less than 90% of the standard.

Receptor binding assay: Meets quality standards

3. Stability data :

Long-term stability : Stored at -20℃ for 24 months, all indicators meet the requirements.

Accelerated testing : After being stored at 25°C for 6 months, the purity decreased by ≤2.0%.

Stability in use : After reconstitution, store at 2-8℃ for 7 days; purity ≥95%.

Scientific Research Applications and Clinical Prospects

1. Mechanism of action study :

Pulse release : Regulating the pulse release mode of GnRH

Gonadal axis regulation : regulating the function of the hypothalamus-pituitary-gonadal axis

Metabolic Connections : Exploring the Interactions Between Metabolism and Reproductive Function

2. Research and application areas :

Reproductive Medicine : Research on Infertility and Hypogonadism

Neuroendocrine system : initiation of puberty, regulation of the reproductive cycle

Metabolic Research : The Link Between Energy Metabolism and Reproductive Function

3. Preclinical data :

Hormone release : Animal experiments show significant promotion of LH release.

Good safety profile : Endogenous peptide analogs with high biocompatibility.

Pulse characteristics : Simulates physiological pulse release pattern

China's manufacturing quality advantages

1. Advantages in manufacturing process :

Synthesis technology : Microwave-assisted solid-state synthesis with high condensation efficiency.

Purification process : Preparative HPLC purification, collection of the main peak.

Quality control : Quality control throughout the entire process from raw materials to finished products.

2. Quality Assurance System :

Compliant with standards : Meets Chinese Pharmacopoeia, USP, and EP standards.

Stability study : Complete a comprehensive stability investigation.

Batch consistency : Strict process control ensures consistency between batches.

3. Global supply network :

Production Base : GMP-compliant production base in China

Distribution network : A global distribution and cold chain logistics network

Registration support : Supports registration applications from countries around the world.

Why choose Kisspeptin-10 made in China ?

Endogenous substances : Signal peptides naturally present in the human body

Precise Regulation : Specific Regulation of HPG Axis Function

Exceptional purity : Over 98% high purity, with strict quality control.

Stable supply : A complete supply chain ensures timely and reliable delivery.

Summary

Kisspeptin-10 10mg lyophilized powder for injection, made in China, represents a high-quality standard for neuroendocrine research tools . Through advanced synthesis processes, rigorous quality control, and a stable supply system , it provides high-quality, highly active research tools for reproductive endocrinology and neuroscience research worldwide . Choosing "Made in China" means choosing research-grade quality and reliable assurance .

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