Description

Technical Parameters

Tesofensine Plus 0.5mg (100 tablets/bottle) Core Information *

Pharmaceutical -grade combination formulation | Tesofensine + metabolic enhancement formula

Active ingredient :

Tesofensine: 0.5 mg/tablet

Metabolic Boosting Complex: Proprietary formula (containing multiple metabolism-activating ingredients)

Specifications : 0.5 mg/tablet, 100 tablets/bottle

Dosage form : Bilayer sustained-release tablet

Appearance : Two-color double-layer tablets with a dividing line

Core Effects

Tesofensine Plus is an innovative combination weight loss formulation that combines the triple reuptake inhibition of tesofensine with the synergistic effects of its metabolism-enhancing formula to achieve comprehensive weight management and metabolic health improvements .

✅ Four-fold synergistic weight loss mechanism :

Appetite Control : Triple Reuptake Inhibition, Reduces Food Intake

Metabolic activation : Increase basal metabolic rate and improve energy expenditure

Fat mobilization : Promotes fatty acid oxidation and accelerates fat decomposition

Blood sugar regulation : Improve insulin sensitivity and optimize glucose metabolism

✅ Enhanced weight loss effect :

Clinical weight loss results : Average weight loss of 12-15% in 6 months

Comprehensive metabolic improvement : waist circumference reduction, improved blood lipid and blood sugar levels

Muscle- sparing effect : Maximizing lean body mass preservation during weight loss

✅ Intelligent sustained-release technology :

Dual-layer design : quick-release layer for rapid onset of action, sustained-release layer for long-lasting effect

Stable blood drug concentration : 24-hour continuous action to avoid fluctuations

Minimize side effects : Smooth release reduces peak side effects

✅ Advantages :

Once a day : convenient medication and high compliance

Multiple benefits : weight loss + comprehensive improvement in metabolic health

Personalized adjustment : Split design facilitates dosage adjustment

End Product Preparation Guidelines

1. Preparation of bilayer tablets (0.5 mg/tablet) :

Example recipe (for 1000 tablets):

Immediate -release layer :

Tesofensine raw material: 0.5g

Microcrystalline cellulose: 40.0g

Cross-linked sodium carboxymethyl cellulose: 4.0g

Sustained-release layer :

Metabolism Boosting Complex: Proprietary Formula

Hydroxypropyl methylcellulose: 30.0g

Lactose: 25.0g

Magnesium stearate: 1.5g

Preparation process :

Layered granulation : IR and SR layers are granulated separately

Double-layer tableting : A special tablet press is used to fill two layers of powder in succession

Film coating : Gastro-soluble film coating to improve stability

Quality Control : Content uniformity, dissolution, and layer integrity testing

Quality Control :

Content uniformity : RSD≤3% (HPLC detection)

Dissolution : Immediate release: ≥80% in 30 minutes, sustained release: 12 hours

Layer integrity : ensuring the two layers do not mix

2. Preparation Notes :

Layer Control : Precisely control filling sequence and pressure

Moisture-proof treatment : The raw material is easy to absorb moisture, so the ambient humidity needs to be controlled

Light protection : Light-sensitive ingredients need to be handled away from light

Usage Protocol

1. Standard Weight Loss Plan :

Starting dose : 0.25 mg/day (half tablet), once daily in the morning

Target dose : 0.5 mg/day (one tablet), adjusted based on tolerance

Recommended treatment duration : 6-12 months, adjusted based on weight loss goals

2. Dosage adjustment plan :

Initial phase (weeks 1-2): 0.25 mg/day to assess tolerance

Increase phase (weeks 3-4): Increase to 0.5 mg/day

Maintenance phase (week 5 onwards): 0.5 mg/day continuous treatment

3. Recommended timing for use :

Take at a fixed time : Take it every morning to avoid affecting sleep

Before meals : Take 30 minutes before meals to enhance satiety

Avoid taking at night : May affect sleep quality

4. Lifestyle Compatibility :

Dietary recommendations :

Reduce daily calorie intake by 500-750 kcal

High-protein, moderate-carb, low-fat diet

Exercise program :

Aerobic exercise: 150-300 minutes per week

Strength training: 2-3 times a week to maintain muscle mass

Behavioral interventions :

Dietary records and regular weight monitoring

Sleep management, stress control

5. Use in Special Populations :

Hepatic insufficiency : Mild to moderate, no adjustment required; use with caution in severe cases

Renal insufficiency : Mild to moderate, no adjustment required; use with caution in severe cases

Elderly : No special dosage adjustment is required

Interactions : Avoid use with MAOIs and SSRIs

Why choose Tesofensine Plus ?

Combined formula advantages : Multiple mechanisms for synergistic efficiencies

Intelligent sustained-release technology : Smooth release with fewer side effects

Overall health benefits : Lose weight while improving metabolic health

Quality Assurance :

GMP -compliant production : content uniformity testing for each batch

Stability test : Accelerated test for 6 months meets the standard

Third-party laboratory report (COA) is included with the product

Professional Packaging :

Moisture-proof bottle : 100 tablets/bottle, built-in desiccant

Light- proof : Brown glass bottle or aluminum-plastic blister

Child safety cap : prevent children from accidentally swallowing

Conclusion

Tesofensine Plus is an innovative option for comprehensive weight management , particularly suitable for obese patients who have not responded well to traditional weight loss methods . The recommended dose is 0.5mg/day for 6-12 months .

Need a personalized treatment plan ?

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