Description

Technical Parameters

HEPIUS brand dutasteride 250mcg 100 tablets core introduction *

Pharmaceutical-grade formulation | HEPIUS brand dutasteride

Chemical name : (5α,17β)-N-{2,5-bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide

CAS No .: 164656-23-9

Specifications : 250mcg/tablet, 100 tablets/bottle

Dosage form : Film-coated tablets

Molecular formula : C₂₇H₃₀F₆N₂O₂

Molecular weight : 528.54

Melting point : 242-245℃

Appearance : White, round tablets with dividing lines.

Purity : ≥99% (HPLC detection)

Core Function | Core Effects

HEPIUS brand dutasteride is a dual 5α-reductase inhibitor . Due to its unique property of simultaneously inhibiting type I and type II 5α-reductase , it is widely used in the treatment of benign prostatic hyperplasia, the control of androgenetic alopecia, and the management of dihydrotestosterone-related diseases .

✅ Dual inhibition mechanism :

Type I inhibition : Inhibition of type I 5α-reductase in extratesticular tissues.

Type II inhibition : Strongly inhibits type II 5α-reductase in prostate tissue.

DHT reduction : Significantly reduces serum and tissue levels of dihydrotestosterone.

✅ HEPIUS Brand Unique Advantages :

Purity Guarantee : Raw material purity ≥ 99.5%, meeting pharmacopoeia standards.

Crystal form control : Stable α-crystal form ensures consistent dissolution.

China GMP Production : Production strictly adheres to China's GMP standards.

✅ Advantages in clinical application :

Dual inhibition : Simultaneous inhibition of both type I and type II 5α-reductase

Highly effective at lowering DHT : Reduces DHT levels by ≥90%

Long-lasting effect : With a half-life of up to 5 weeks, it is suitable for long-term treatment.

HEPIUS Brand Quality Advantages

1. Raw material quality control :

Chemical purity : Raw material purity ≥ 99.5% (HPLC detection)

Chirality control : Optical purity of the four chiral centers ≥ 99.8%

Impurity control : Single unknown impurity <0.05%, total impurities <0.1%

2. Advantages in formulation technology :

Micronization technology : Raw material particle size D90≤10μm, ensuring uniformity at low dosages.

Multi-layer coating system :

Isolation layer: Moisture-proof and oxidation-proof protection

Sustained-release layer: controls the release rate

Protective layer: Gastric coating

Content uniformity : RSD ≤ 1.5% (Pharmacopoeia requirement ≤ 6%)

3. Production Quality System :

GMP Certification : China GMP Certified Production Facilities

Environmental control : Class 100,000 cleanroom, online particle monitoring

Quality Traceability : A Full-Process Electronic Traceability System from Raw Materials to Finished Products

4. Quality control indicators :

Content accuracy : 250mcg ± 5% (HPLC detection)

Dissolution rate : ≥80% dissolution after 30 minutes, ≥85% dissolution after 45 minutes.

Related substances : Degradation products <0.1%, total impurities <0.2%

Stability : Passed accelerated testing after 6 months; shelf life: 36 months.

HEPIUS Brand Clinical Advantages

1. Therapeutic advantages :

Potent inhibition : Clinical studies show a DHT reduction of ≥90%.

Prostate volume : Significantly reduced prostate volume by 20-30%.

Hair loss treatment : Effectively improves androgenetic alopecia

2. Key Features and Advantages :

Dual inhibition : The only enzyme that simultaneously inhibits both type I and type II 5α-reductase

Long-lasting effect : Half-life up to 5 weeks, stable blood drug concentration.

Tissue distribution : High concentration in the prostate, with strong targeting.

3. Advantages of use :

Convenient administration : once daily oral administration, resulting in high patient compliance.

Precise dosage : 250mcg low dose, with definite therapeutic effect.

Long-term management : Suitable for long-term treatment of chronic diseases

Why choose HEPIUS brand dutasteride?

Dual inhibition : Simultaneously inhibits both type I and type II 5α-reductase

Powerful DHT Lowering : Reduces DHT levels by ≥90%

Made in China : GMP-standard production, reliable quality

Long -lasting and convenient : With a half-life of up to 5 weeks, it is easy to administer.

Summarize

HEPIUS brand dutasteride 250mcg tablets represent the high-quality standard of 5α-reductase inhibitors . Through advanced manufacturing processes, strict quality control, and a stable supply system , HEPIUS provides a high-quality, high-efficiency treatment option for patients with benign prostatic hyperplasia and androgenetic alopecia . Choosing HEPIUS means choosing Chinese quality and reliable assurance .

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