Description

Technical Parameters

STADA brand letrozole 2.5mg 50 tablets core introduction *

Pharmaceutical-grade formulation | STADA brand letrozole (non-steroidal aromatase inhibitor)

Chemical name : 4,4'-(1H-1,2,4-triazol-1-ylmethylene)dibenzonitrile

CAS No .: 112809-51-5

Specifications : 2.5mg/tablet, 50 tablets/bottle

Dosage form : Film-coated tablets

Molecular formula : C₁₇H₁₁N₅

Molecular weight : 285.31

Melting point : 181-183℃

Appearance : White, round tablets with dividing lines.

Purity : ≥99% (USP standard HPLC test)

Core Function | Core Effects

STADA brand letrozole is a highly selective nonsteroidal aromatase inhibitor . Due to its potent estrogen-inhibiting activity and high specificity , it is widely used in endocrine therapy for breast cancer and in the prevention and control of estrogen-related side effects .

✅Powerful inhibition mechanism :

High selectivity : Specifically inhibits aromatase without affecting the synthesis of adrenocortical hormones.

Non-steroidal structure : Reversibly binds to aromatase, competitively inhibiting estrogen conversion.

Potent inhibition : A single dose can reduce estrogen levels in the body by over 75%.

✅ STADA's unique brand advantages :

Purity Guarantee : Raw material purity ≥ 99.5%, conforming to USP standards.

Crystal form control : Stable α-crystal form ensures consistent dissolution.

Manufacturing under US cGMP standards : Strictly adheres to US FDA cGMP standards.

✅ Advantages in clinical application :

Potent inhibition : Effectively reduces plasma estrogen levels

High selectivity : Does not affect the synthesis of adrenocortical hormones

Oral administration is convenient : once-daily dosing leads to high patient compliance.

STADA Brand Quality Advantages

1. Raw material quality control :

Chemical purity : Raw material purity ≥ 99.5% (HPLC detection, conforming to USP standards)

Isomer control : Ensuring the correct configuration of the triazole ring

Impurity control : Single unknown impurity <0.05%, total impurities <0.1%

2. Advantages in formulation technology :

Micronization technology : Raw material particle size D90≤10μm, ensuring rapid dissolution.

Multi-layer coating system :

Isolation layer: Moisture-proof and oxidation-proof protection

Sustained-release layer: controls the release rate

Protective layer: Gastric coating

Anti-counterfeiting technology : Holographic anti-counterfeiting label, scan code to verify authenticity.

3. Production Quality System :

cGMP Certification : US FDA cGMP certified production facility

Environmental control : ISO Class 5 cleanroom, online particle monitoring

Quality Traceability : A Full-Process Electronic Traceability System from Raw Materials to Finished Products

4. Quality control indicators :

Content uniformity : RSD ≤ 1.5% (USP standard requires ≤ 6%)

Dissolution rate : ≥80% dissolution after 30 minutes, ≥85% dissolution after 45 minutes.

Related substances : Degradation products <0.1%, total impurities <0.2%

Stability : Passed accelerated testing after 6 months; shelf life: 36 months.

STADA Brand Clinical Advantages

1. Advantages in effectiveness :

Potent inhibition : A single dose can reduce estrogen levels by over 75%.

Rapid onset of action : Peak blood plasma concentration is reached 1 hour after oral administration.

Long-lasting inhibition : Half-life of approximately 45 hours, suitable for once-daily dosing.

2. Key Features and Advantages :

High selectivity : Specifically inhibits aromatase without affecting the synthesis of other steroid hormones.

Non-steroidal structures : have no affinity for estrogen receptors and do not have estrogen-like effects.

Good safety profile : Does not inhibit adrenocortical hormone synthesis

3. Advantages of use :

Oral administration is convenient : once-daily dosing leads to high patient compliance.

Flexible dosage : The daily dose can be adjusted from 1.25 to 2.5 mg.

Long-term safety : Suitable for long-term adjunctive endocrine therapy

Why choose STADA brand letrozole?

Powerful inhibition : Effectively reduces estrogen levels by over 75%

High selectivity : Specifically inhibits aromatase, with good safety profile.

Made in the USA : Manufactured to cGMP standards, ensuring reliable quality.

Convenient oral administration : once-daily dosing, high compliance.

Summarize

STADA brand letrozole 2.5mg tablets represent the high-quality standard of highly selective aromatase inhibitors . Through advanced manufacturing processes, strict quality control, and a stable supply system , STADA provides a high-quality, high-efficiency product option for breast cancer patients and athletes who require potent estrogen suppression . Choosing STADA means choosing American quality and precision medicine .

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