Description

Technical Parameters

MK -677 (Ibumolen) Raw Material Powder Product Introduction

Pure Research-Based Ingredients | MK-677 (Ibutamoren Mesylate) Growth Hormone Secretagogue

Chemical name : 2-Isopropyl-1-[(2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]piperidine-4-carboxylic acid methyl ester methanesulfonate

CAS No .: 159752-10-0

Molecular formula : C₂₅H₃₂N₄O₂ • CH₄O₃S

Molecular weight : 512.62

Purity : ≥98% (HPLC)

Melting point : 191°C-195°C

Appearance : White or off-white crystalline powder

Usage

MK-677 (Ibumolem) is a non-peptide growth hormone secretagogue receptor agonist . It mimics the effects of hunger hormone (ghrelin) and is widely used for muscle growth, fat loss, sleep improvement, and anti-aging .

✅ Promote the secretion of growth hormone :

Mimics the effects of Ghrelin , stimulating the pituitary gland to release growth hormone and IGF-1

Increase GH levels by 2-3 times and IGF-1 levels by 50-80%

✅ Body Recomposition Effects :

Increase lean body mass while reducing body fat

Improve bone density and joint health

✅ Improved quality of life :

Improve deep sleep and increase slow-wave sleep time

Improve skin and hair quality and reduce wrinkles

MK -677 (Ibumolun) Features

Oral high efficacy :

High oral bioavailability (>80%)

Take once a day , no injection required

Long-lasting effect :

24- hour half-life , providing sustained growth hormone stimulation

Simulates natural pulsatile GH secretion

High security :

Non- hormonal compounds that do not inhibit the secretion of one's own hormones

No estrogenic/androgenic side effects

Multiple benefits :

Improve body composition, sleep and recovery simultaneously

Long-term use has cumulative effects

End Product Preparation Guidelines

Best finished product form :

Oral tablets (preferred) :

Concentration : 10mg/tablet or 25mg/tablet

Formula : Microcrystalline Cellulose + Croscarmellose Sodium + Magnesium Stearate

Advantages : Accurate dosage, easy to use, good stability

Oral solution (alternative option) :

Concentration : 10mg/mL

Solvent : PEG-400 + ethanol (10%) + flavoring

Advantages : Rapid absorption, suitable for dosage adjustment

Sublingual tablets (high-potency option) :

Concentration : 5mg/tablet

Features : Avoids first-pass effect and increases bioavailability by 30%

Preparation process flow :

Raw material pretreatment :

Micronization treatment (D90≤10μm) to improve dissolution

Tablet preparation :

Wet granulation : Ensure content uniformity (RSD ≤ 3%)

Film coating : Improving stability and palatability

Quality Control :

HPLC test : Purity ≥ 98%, content uniformity meets the standard

Dissolution test : ≥85% dissolved in 30 minutes

MK -677 (Ibumolen) Applications

Muscle Building :

Dosage : 25 mg/day, taken before bed

Cycle : Continuous use for 3-6 months

Fat Loss :

Dosage : 10-15 mg/day, combined with aerobic exercise

Effect : Targeted reduction of abdominal fat

Anti -Aging :

Dosage : 10 mg/day for long-term use

Improved : Skin elasticity, sleep quality, and energy levels

Precautions

⚠ Blood sugar impact : May temporarily increase insulin resistance (blood sugar monitoring recommended)

⚠ Hunger : May stimulate appetite (can be managed through meal planning)

⚠ Water and sodium retention : mild edema (usually adapts after 2-3 weeks)

Why choose MK-677 raw material ?

Non-hormonal growth hormone promoter , high safety

Multiple benefits , improving body composition and sleep quality

Flexible preparation , multiple dosage forms can be developed to meet different needs

Quality Assurance :

GMP -compliant production , each batch HPLC purity tested (≥98% )

Third-party laboratory report (COA) is included with the goods

Aseptic production process to ensure safety

Worldwide Shipping :

Original sealed packaging , moisture-proof and light-proof

Private delivery , no logo on the outer packaging

Temperature- stable transportation to ensure product stability

Conclusion

MK-677 is a revolutionary choice for growth hormone optimization , particularly suitable for the formulation of oral tablets to achieve muscle growth, fat loss, and anti-aging effects . The recommended end-product dosage is 10-25mg/day .

Need a specific preparation plan ?

We provide professional technical guidance to help you prepare end products safely and efficiently!

Special Tips :

This product must be prepared in a clean environment that complies with GMP standards to ensure product quality and safety. Human use may affect blood sugar levels. Diabetic patients should consult a physician before use.

If you need anything, please contact Allen