Description

Technical Parameters

Benzocaine (Benzocaine) Raw Material Powder Core Introduction

Pharmaceutical Grade Ingredients | Benzocaine (Local Anesthetic )

Chemical name : Ethyl p-aminobenzoate

CAS number : 94-09-7

Molecular formula : C₉H₁₁NO₂

Molecular weight : 165.19

Melting point : 88-92°C

Appearance : White crystalline powder

Purity : ≥99% (HPLC)

Core Effects

Benzocaine is a topical anesthetic . Due to its strong surface anesthetic effect and rapid onset of action , it is widely used for surface anesthesia of the skin and mucous membranes, analgesia and itching relief, and various topical preparations .

✅ Rapid surface anesthesia :

Blocks nerve impulse conduction and takes effect quickly within 1-3 minutes

The anesthetic effect is long-lasting and lasts for 30-60 minutes

✅ Multiple application scenarios :

Skin itching and pain relief : Relieve pain from insect bites and mild burns

Oral mucosal anesthesia : relief of oral ulcers and gingival swelling and pain

Sports Injury Care : Topical Pain Relief for Muscle Soreness and Sprains

✅ Safety features :

Not easily absorbed through the skin , low risk of systemic toxicity

Local effect , does not affect the physiological functions of the whole body

✅ Advantages :

Fast- acting , immediate pain relief

Easy to use , easy to handle topical preparations

High safety , wide therapeutic index, and few side effects

End Product Preparation Guidelines

1. Preparation of topical cream (5%) :

Recipe example (1000g preparation):

Benzocaine raw material: 50.0g

Stearic acid: 100.0g

Glyceryl monostearate: 30.0g

White vaseline: 150.0g

Glycerin: 50.0g

Triethanolamine: appropriate amount

Purified water: add to 1000g

Preparation process :

Oil phase preparation : Stearic acid, glyceryl monostearate, and petrolatum are heated and melted (70-75°C)

Water phase preparation : glycerol, triethanolamine, and purified water are heated to the same temperature

Emulsification and mixing : Slowly add the oil phase to the water phase and stir to emulsify

Add the main drug : When the temperature drops to 50°C, add benzocaine powder

Homogenization and cooling : Stir with a homogenizer and cool to room temperature

Quality Control :

Content uniformity : RSD≤5% (UV detection)

pH : 5.5-7.0

Microbial limits : Comply with pharmacopoeia regulations

2. Preparation of oral spray (10%) :

Recipe example (preparation volume for 100ml):

Benzocaine raw material: 10.0g

Ethanol: 30.0ml

Glycerol: 10.0ml

Menthol: 0.5g

Purified water: add to 100ml

Usage Protocol

1. For external use on skin :

Applicable symptoms :

Insect bites, minor burns, sunburn

Skin itching, pain from mild trauma

How to use :

Apply appropriate amount of cream to the affected area 3-4 times a day

Maximum usable area: within 10% of body surface area

Usage Notes :

Avoid use on broken skin

If an allergic reaction occurs, stop use immediately

2. Oral application :

Applicable symptoms :

Oral ulcers, swollen and painful gums

Denture discomfort, analgesia before and after oral surgery

How to use :

Spray: spray 1-2 times on the affected area, no more than 4 times a day

Gel: Apply an appropriate amount on the affected area with a cotton swab

Usage Notes :

Avoid eating or drinking within 30 minutes after use

Do not use more than 4 times in 24 hours

3. Sports Injury Care :

Application Situations :

Muscle soreness, sprains, and strains

Joint pain, recovery after exercise

How to use :

Apply and massage on the painful area 2-3 times a day

Can be combined with bandage to enhance the effect

4. Use in special populations :

Children's Use :

Not suitable for children under 2 years old

Children aged 2-12 years should use a reduced dose

Pregnant women and breastfeeding :

Use under doctor's guidance when necessary

Avoid long-term and large-area use

Why choose benzocaine ?

Fast and effective , takes effect quickly in 1-3 minutes, and relieves pain immediately

Safe to use , local effect, little systemic absorption, and few side effects

Widely used in many scenarios such as skin, oral, sports injuries, etc.

Quality Assurance :

GMP -compliant production , each batch HPLC purity tested (≥99% )

Stability study : Accelerated test for 6 months meets the standard

Third-party laboratory report (COA) is included with the product

Professional Packaging :

Moisture-proof and light-proof packaging : aluminum foil bag + desiccant

Normal temperature transportation : transport at 15-25°C

Privacy delivery : No sensitive information on the outer packaging

Conclusion

Benzocaine is an important choice for local anesthesia and analgesia , particularly suitable for skin and mucosal surface anesthesia, oral analgesia, and sports injury care . The recommended concentration is 2-20% , which can be adjusted according to the application.

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