Description

Technical Parameters

Kisspeptin 10mg/bottle Core Introduction

Research -grade freeze-dried powder | Kisspeptin-10 neuropeptide hormone

Amino acid sequence : Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂

Molecular weight : approximately 1,147 Da

Purity : ≥97% (HPLC)

Specifications : 10mg/bottle

Appearance : White freeze-dried powder

Solvent : 1mL bacteriostatic water

Core Effects

Kisspeptin is a key neuropeptide hormone that is widely used in reproductive endocrinology research, gonadal function assessment, and neuroendocrine research due to its core regulatory role in the hypothalamic-pituitary-gonadal axis (HPG axis) .

✅ HPG axis core regulation :

Stimulates the release of GnRH and promotes the secretion of LH and FSH by the pituitary gland

Initiate puberty and regulate sexual maturation

✅ Reproductive function regulation :

Promote ovulation for assisted reproductive technology

Improve sperm production and treat male infertility

✅ Neuroendocrine effects :

Regulate energy metabolism and connect reproduction and metabolic balance

Affect emotional behavior and participate in stress response regulation

✅ Advantages :

Physiological regulation , simulating the natural hormone secretion rhythm

High specificity , precise targeting of the reproductive endocrine axis

End Product Preparation Guidelines

1. Preparation of injection (1 mg/mL) :

Recipe Example (makes 10 bottles):

Kisspeptin-10 raw material: 10mg

Mannitol: 100 mg

Sodium acetate buffer (pH 4.0): add to 10 mL

Preparation process :

Buffer preparation : pH 4.0 sodium acetate buffer

Dissolve and mix : Stir gently to dissolve, avoiding bubbles

Sterile filtration : 0.22μm membrane low pressure filtration

Freeze -dried : 1 mL per bottle, vacuum freeze-dried

Quality Control :

Biological activity : GnRH release stimulating activity assayed by cell-based assay

Purity test : RP-HPLC test purity ≥97%

Sterility test : Membrane filtration method for 14 days

2. Preparation Notes :

Temperature control : 2-8°C low temperature operation throughout the process

Avoid oxidation : Nitrogen protection to prevent methionine oxidation

Lyophilization process : Slow heating to avoid damage to peptide structure

Usage Protocol

1. Recombination method :

Use 1mL of bacteriostatic water to slowly inject into the wall of the freeze-dried powder bottle

Gently swirl until completely dissolved; avoid vigorous shaking or vortexing

Storage after reconstitution : Refrigerate at 2-8°C and use within 7 days

2. Injection method :

Injection route : Subcutaneous injection or intravenous injection

Injection dose :

Diagnostic use : 0.2-1.0 μg/kg, single injection

Therapeutic use : 1-10 μg/kg, pulse dosing

Injection frequency :

Pulse dosing : Injection every 60-90 minutes

Treatment cycle : Continuous pulse administration for 2-4 weeks

3. Treatment options :

Diagnosis of reproductive dysfunction :

Single injection of 0.2-1.0 μg/kg

Monitor LH pulse secretion after injection

Assisted reproductive treatment :

Pulse dosing, 1-3 μg/kg every 90 minutes

Continuous treatment for 2-4 weeks to induce ovulation or spermatogenesis

Storage Guidelines

1. Unrestored :

Temperature : -20°C for long-term storage, 2-8°C for short-term storage

Humidity : Relative humidity ≤ 30%, desiccant protection

Light : Store away from light, in brown glass bottle or wrapped in aluminum foil

Expiration date : 24 months at -20°C, 12 months at 2-8°C

2. Storage after reconstitution :

Use Immediately : For best results, use immediately after reconstitution

Store in refrigerator : 2-8°C for no more than 7 days

Avoid freezing : reconstituted solutions should not be repeatedly frozen and thawed

3. Transport Conditions :

Ultra- low temperature transport : dry ice transport (-78°C)

Shockproof packaging : prevents severe vibrations from affecting the peptide structure

Fast delivery : Delivery within 48 hours to ensure activity

Why choose Kissin ?

Key regulatory factors of the HPG axis , core tools for reproductive endocrinology research

Physiological regulation , closer to natural physiological rhythm

Multiple application values , from basic research to clinical treatment

Quality Assurance :

GMP -compliant production , each batch HPLC purity tested (≥97% )

Third-party laboratory report (COA) is included with the product

Sterile freeze-drying process to ensure no endotoxin

Worldwide Shipping :

Medical vial packaging , rubber stopper seal

Dry ice transportation to ensure peptide activity

Private delivery , no logo on the outer packaging

Conclusion

Kissin is an advanced tool for reproductive endocrinology research , particularly suitable for HPG axis function research, reproductive dysfunction diagnosis and assisted reproductive treatment . The recommended dose is 0.2-10μg/kg .

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